Review of pharmaceutical applications of N-methyl-2-pyrrolidone.

نویسندگان

  • Abolghasem Jouyban
  • Mohammad A A Fakhree
  • Ali Shayanfar
چکیده

N-Methyl-2-pyrrolidone (NMP) or Pharmasolve is very strong solubilizing agent and it has important applications in different fields of industry. This review presents NMP physicochemical characteristics, application especially in pharmaceutical sciences, pharmacokinetic and toxicity. Characteristics of NMP such as physicochemical properties, solubilization efficacy, toxicity and adverse effects were compared with other common solvents used in the pharmaceutical industries. This review reveals that NMP is an acceptable pharmaceutical solvent and its efficacy, toxicity, and side effects are comparable with other common solvent.

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عنوان ژورنال:
  • Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques

دوره 13 4  شماره 

صفحات  -

تاریخ انتشار 2010